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KMID : 0381219940260040186
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Journal of RIMSK
1994 Volume.26 No. 4 p.186 ~ p.192
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Neurogenic Complications of Hypertension
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Abstract
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neurogenic mechanisms are important in the maintenance of most form of hypertension, yet the brain is highly vulnerable to the deleterious effects of elevated blood pressure. Hypertensive encephalopathy results from a sudden, sustained rise in
blood
perssure sufficient to exceed the upper limit of cerebral blood flow autoregulation. Major cerebral vascular complications during hypertension may be largely due to endothelial dysfunction. Stroke is a generic term for clinical syndrome that
include
focal infarction or hemorrhage in the brain, or subarachnoid hemorrhage. Atherothromboembolism and thrombotic occlusion of lipohyalynotic small-diameter end arteries are the pricncipal cause of cerebral infarction Microaneurysm rupture is the
usual
cause of hypertension-associated intracerebral hemorrhage. Rupture is the usual cause of hypertension-associated intracerebral hemorrhage. Rupture of aneurysm on the circle of Willis is the most common cause of nontraumatic subarachnoid
hemorrhage.
Stroke is a major cause of morbidity and mortality, particularly among persons aged 65 years or older. Treatment of diastolic hypertension reduces than incidence of stroke by about 40% Treatment of isolated systoic hypertension in persons aged 60
years
and older reduces the incidence of stroke by more the one third. Blood pressure management in the setting of acute stroke and the role of antihypertrtensive theraphy in the prevention of acute stroke and the role of antihypetihypetrtensive
theraphy
in
the prevention of multi-infarct dementia require further study.
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KEYWORD
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